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Dynamic Covalent Chemistry in Fragment-based Drug Design

Gray, M; Harburn, J.J

Authors

M Gray

J.J Harburn



Abstract

In recent years Dynamic Covalent Chemistry (DCC) has transformed from being an academic curiosity to become an invaluable tool in the creation of functional systems. This contribution examines the role DCC has played over the past decade in Drug Discovery and, in particular, explores the synergy that has become apparent with Fragment Based Lead Discovery.

Citation

Gray, M., & Harburn, J. (2011). Dynamic Covalent Chemistry in Fragment-based Drug Design. https://doi.org/10.1081/e-esmc-120045517

Journal Article Type Article
Publication Date 2011
Deposit Date Oct 26, 2012
Peer Reviewed Peer Reviewed
Pages 1-9
DOI https://doi.org/10.1081/e-esmc-120045517
Keywords Dynamic Covalent Chemistry, Dynamic Combinatorial Chemistry, DCC, Fragment Based Drug Discovery, FBDD, Fragment Based Lead Discovery, FBLD.

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