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Durham Research Online
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Dynamic covalent chemistry in fragment-based drug design.

Gray, M. and Harburn, J.J (2011) 'Dynamic covalent chemistry in fragment-based drug design.', in Encyclopedia of supramolecular chemistry. London: Taylor & Francis, pp. 1-9.

Abstract

In recent years Dynamic Covalent Chemistry (DCC) has transformed from being an academic curiosity to become an invaluable tool in the creation of functional systems. This contribution examines the role DCC has played over the past decade in Drug Discovery and, in particular, explores the synergy that has become apparent with Fragment Based Lead Discovery.

Item Type:Book chapter
Keywords:Dynamic Covalent Chemistry, Dynamic Combinatorial Chemistry, DCC, Fragment Based Drug Discovery, FBDD, Fragment Based Lead Discovery, FBLD.
Full text:Full text not available from this repository.
Publisher Web site:http://dx.doi.org/10.1081/E-ESMC-120045517
Record Created:29 Oct 2012 13:20
Last Modified:02 Nov 2012 15:17

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