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Synthesis of Novel Steroidal Inhibitors of HIV-1 Protease

Harburn, J.J; Loftus, G.C; Marples, B.A

Authors

J.J Harburn

G.C Loftus

B.A Marples



Abstract

The design and synthesis of potential steroidal HIV-1 protease inhibitors is described. Compounds derived from 11-amino-12-keto-cholanic acid derivatives show modest activity.

Citation

Harburn, J., Loftus, G., & Marples, B. (1998). Synthesis of Novel Steroidal Inhibitors of HIV-1 Protease. Tetrahedron, 54(39), 11907-11924. https://doi.org/10.1016/s0040-4020%2898%2900699-1

Journal Article Type Article
Publication Date Sep 1, 1998
Deposit Date Nov 19, 2012
Journal Tetrahedron
Print ISSN 0040-4020
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 54
Issue 39
Pages 11907-11924
DOI https://doi.org/10.1016/s0040-4020%2898%2900699-1