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Synthesis of novel steroidal inhibitors of HIV-1 protease.

Harburn, J.J and Loftus, G.C and Marples, B.A (1998) 'Synthesis of novel steroidal inhibitors of HIV-1 protease.', Tetrahedron., 54 (39). pp. 11907-11924.


The design and synthesis of potential steroidal HIV-1 protease inhibitors is described. Compounds derived from 11-amino-12-keto-cholanic acid derivatives show modest activity.

Item Type:Article
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Record Created:22 Nov 2012 12:05
Last Modified:02 Jan 2013 09:25

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