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Four early clinical studies to assess the effects of Peruvian bark.

Maehle, Andreas-Holger (2013) 'Four early clinical studies to assess the effects of Peruvian bark.', Journal of the Royal Society of Medicine., 106 (4). pp. 150-155.


From the late seventeenth century onwards, in vitro and animal experimentation, chemical tests and microscopical observation, and the analysis of single case histories were used to understand the pharmacology and therapeutic properties of the Peruvian bark. Four examples illustrate how “clinical experiments” with the bark were made during the last third of the eighteenth century: in a hospital, the army, the navy, and finally in private practice.

Item Type:Article
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Publisher statement:The final definitive version of this article has been published in the Journal of the Royal Society of Medicine 106/4, 2013 © The Royal Society of Medicine by SAGE Publications Ltd at the Journal of the Royal Society of Medicine page: on SAGE Journals Online:
Record Created:27 Nov 2013 14:35
Last Modified:07 Jan 2014 14:32

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