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Current directions in co-crystal growth

Blagden, N.; Berry, D.J.; Parkin, A.; Javed, H.; Ibrahim, A.; Gavan, P.T.; De Matos, L.L.; Seaton, C.C.

Authors

N. Blagden

D.J. Berry

A. Parkin

H. Javed

A. Ibrahim

P.T. Gavan

L.L. De Matos

C.C. Seaton



Abstract

In this feature article we will focus on the issues relating to the crystal growth of co-crystals, with a particular emphasis on drug development. The initial focus of this perspective is on the relevant literature examples that may be able to inform our understanding with regards co-crystal crystallisation and the allied supramolecular concepts. The second part of this perspective contains selected examples from our own work, which add to the literature perspective. Topics include; nucleation templates, in situ synchrotron XRD studies, solid-state synthesis through mixing and screening strategies.

Citation

Blagden, N., Berry, D., Parkin, A., Javed, H., Ibrahim, A., Gavan, P., …Seaton, C. (2008). Current directions in co-crystal growth. New Journal of Chemistry, 32(10), 1659-1672. https://doi.org/10.1039/b803866j

Journal Article Type Article
Publication Date Oct 1, 2008
Deposit Date Mar 4, 2013
Journal New Journal of Chemistry
Print ISSN 1144-0546
Electronic ISSN 1369-9261
Publisher Royal Society of Chemistry
Peer Reviewed Peer Reviewed
Volume 32
Issue 10
Pages 1659-1672
DOI https://doi.org/10.1039/b803866j