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The impact of insecticide-treated school uniforms on dengue infections in school-aged children : study protocol for a randomised controlled trial in Thailand.

Wilder-Smith, A. and Byass, P. and Olanratmanee, P. and Maskhao, P. and Sringernyuang, L. and Logan, J.G. and Lindsay, S.W. and Banks, S. and Gubler, D. and Louis, V.R. and Tozan, Y. and Kittayapong, P. (2012) 'The impact of insecticide-treated school uniforms on dengue infections in school-aged children : study protocol for a randomised controlled trial in Thailand.', Trials., 13 (11). p. 212.

Abstract

Background: There is an urgent need to protect children against dengue since this age group is particularly sensitive to the disease. Since dengue vectors are active mainly during the day, a potential target for control should be schools where children spend a considerable amount of their day. School uniforms are the cultural norm in most developing countries, worn throughout the day. We hypothesise that insecticide-treated school uniforms will reduce the incidence of dengue infection in school-aged children. Our objective is to determine the impact of impregnated school uniforms on dengue incidence. Methods: A randomised controlled trial will be conducted in eastern Thailand in a group of schools with approximately 2,000 students aged 7–18 years. Pre-fabricated school uniforms will be commercially treated to ensure consistent, high-quality insecticide impregnation with permethrin. A double-blind, randomised, crossover trial at the school level will cover two dengue transmission seasons. Discussion: Practical issues and plans concerning intervention implementation, evaluation, analysing and interpreting the data, and possible policy implications arising from the trial are discussed. Trial registration: clinicaltrial.gov. Registration number: NCT01563640.

Item Type:Article
Keywords:Dengue, Insecticide-treated clothes, School children, School uniforms, Randomised control trial, Cost effectiveness.
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Status:Peer-reviewed
Publisher Web site:http://dx.doi.org/10.1186/1745-6215-13-212
Publisher statement:© 2012 Wilder-Smith et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Record Created:22 May 2014 10:20
Last Modified:22 May 2014 11:57

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