Confined bilayers passively regulate shape and stress

Staykova, M.; Arroyo, M.; Rahimi, M.; Stone, H.A.

doi:10.1103/physrevlett.110.028101

Confined bilayers passively regulate shape and stress

Staykova, M.; Arroyo, M.; Rahimi, M.; Stone, H.A.

Authors

Dr Margarita Staykova margarita.staykova@durham.ac.uk
Associate Professor

M. Arroyo

M. Rahimi

H.A. Stone

Abstract

Lipid membranes are commonly confined to adjacent subcellular structures or to artificial substrates and particles. We develop an experimental and theoretical framework to investigate the mechanics of confined membranes, including the influence of adhesion, strain, and osmotic pressure. We find that supported lipid bilayers respond to stress by nucleating and evolving spherical and tubular protrusions. In cells, such transformations are generally attributed to proteins. Our results offer insights into the mechanics of cell membranes and can further extend the applications of supported bilayers.

Citation

Staykova, M., Arroyo, M., Rahimi, M., & Stone, H. (2013). Confined bilayers passively regulate shape and stress. Physical Review Letters, 110(2), Article 028101. https://doi.org/10.1103/physrevlett.110.028101

Journal Article Type	Article
Publication Date	Jan 1, 2013
Deposit Date	Sep 3, 2013
Publicly Available Date	Jul 11, 2014
Journal	Physical Review Letters
Print ISSN	0031-9007
Electronic ISSN	1079-7114
Publisher	American Physical Society
Peer Reviewed	Peer Reviewed
Volume	110
Issue	2
Article Number	028101
DOI	https://doi.org/10.1103/physrevlett.110.028101

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Reprinted with permission from the American Physical Society: Phys. Rev. Lett. 110, 028101 © (2013) by the American Physical Society. Readers may view, browse, and/or download material for temporary copying purposes only, provided these uses are for noncommercial personal purposes. Except as provided by law, this material may not be further reproduced, distributed, transmitted, modified, adapted, performed, displayed, published, or sold in whole or part, without prior written permission from the American Physical Society.