A microgripper sensor device capable of detecting ion efflux from whole cells

Daunton, R.; Wood, D.; Gallant, A.J.; Kataky, R.

doi:10.1039/c4ra05052e

A microgripper sensor device capable of detecting ion efflux from whole cells

Daunton, R.; Wood, D.; Gallant, A.J.; Kataky, R.

Authors

R. Daunton

D. Wood

Professor Andrew Gallant a.j.gallant@durham.ac.uk
Professor

Professor Ritu Kataky ritu.kataky@durham.ac.uk
Professor

Abstract

Electrothermally actuated microgripper sensor devices that are capable of simultaneous manipulation of live mouse oocytes and the sensing of potassium ion efflux are presented. The ion selective electrode technology applied to a microgripper device yielded a first generation ion sensor with competitive characteristics in selectivity, sensitivity, stability and temporal resolution. The microgripper sensor devices could readily detect the 9 ± 3 mM efflux of potassium ions upon mechanical stimulation. This technology is generic and applicable to generating potentiometric and amperometric sensing microgrippers.

Citation

Daunton, R., Wood, D., Gallant, A., & Kataky, R. (2014). A microgripper sensor device capable of detecting ion efflux from whole cells. RSC Advances, 4(92), 50536-50541. https://doi.org/10.1039/c4ra05052e

Journal Article Type	Article
Acceptance Date	Oct 2, 2014
Online Publication Date	Oct 3, 2014
Publication Date	Oct 3, 2014
Deposit Date	Oct 31, 2014
Publicly Available Date	Nov 4, 2014
Journal	RSC Advances
Publisher	Royal Society of Chemistry
Peer Reviewed	Peer Reviewed
Volume	4
Issue	92
Pages	50536-50541
DOI	https://doi.org/10.1039/c4ra05052e