Cookies

We use cookies to ensure that we give you the best experience on our website. By continuing to browse this repository, you give consent for essential cookies to be used. You can read more about our Privacy and Cookie Policy.


Durham Research Online
You are in:

A procedure for the preparation and isolation of nucleoside-5’-diphosphates.

Korhonen, H. J. and Bolt, H. L. and Hodgson, D. R. W. (2015) 'A procedure for the preparation and isolation of nucleoside-5’-diphosphates.', Beilstein journal of organic chemistry., 11 . pp. 469-472.

Abstract

Tris[bis(triphenylphosphoranylidene)ammonium] pyrophosphate (PPN pyrophosphate) was used in the SN2 displacements of the tosylate ion from 5’-tosylnucleosides to afford nucleoside-5’-diphosphates. Selective precipitation permitted the direct isolation of nucleoside-5’-diphosphates from crude reaction mixtures.

Item Type:Article
Keywords:NDP synthesis, Nucleic acids, Nucleoside-5’-diphosphate, Phosphorylation.
Full text:(VoR) Version of Record
Available under License - Creative Commons Attribution.
Download PDF
(220Kb)
Status:Peer-reviewed
Publisher Web site:http://dx.doi.org/10.3762/bjoc.11.52
Publisher statement:© 2015 Korhonen et al; licensee Beilstein-Institut. This is an Open Access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Date accepted:25 March 2015
Date deposited:14 April 2015
Date of first online publication:April 2015
Date first made open access:No date available

Save or Share this output

Export:
Export
Look up in GoogleScholar