Korhonen, H. J. and Bolt, H. L. and Hodgson, D. R. W. (2015) 'A procedure for the preparation and isolation of nucleoside-5’-diphosphates.', Beilstein journal of organic chemistry., 11 . pp. 469-472.
Tris[bis(triphenylphosphoranylidene)ammonium] pyrophosphate (PPN pyrophosphate) was used in the SN2 displacements of the tosylate ion from 5’-tosylnucleosides to afford nucleoside-5’-diphosphates. Selective precipitation permitted the direct isolation of nucleoside-5’-diphosphates from crude reaction mixtures.
|Keywords:||NDP synthesis, Nucleic acids, Nucleoside-5’-diphosphate, Phosphorylation.|
|Full text:||(VoR) Version of Record|
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|Publisher Web site:||http://dx.doi.org/10.3762/bjoc.11.52|
|Publisher statement:||© 2015 Korhonen et al; licensee Beilstein-Institut. This is an Open Access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.|
|Date accepted:||25 March 2015|
|Date deposited:||14 April 2015|
|Date of first online publication:||April 2015|
|Date first made open access:||No date available|
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