Heck-Mizoroki Coupling of Vinyliodide and Applications in The Synthesis of Dienes and Trienes

Whiting, Andrew; Madden, Katrina S.; David, Sylvain; Knowles, Jonathan P.

doi:10.1039/c5cc03273c

Heck-Mizoroki Coupling of Vinyliodide and Applications in The Synthesis of Dienes and Trienes

Whiting, Andrew; Madden, Katrina S.; David, Sylvain; Knowles, Jonathan P.

Authors

Professor Andrew Whiting andy.whiting@durham.ac.uk
Emeritus Professor

Katrina S. Madden

Sylvain David

Jonathan P. Knowles

Abstract

Vinyliodide reacts chemoselectively under Heck-Mizoroki conditions with terminal alkenes, including vinylboronate esters, to give dienes. The resulting dienylboronates undergo Suzuki-Miyaura coupling with aryl, heteroaryl and alkenyl halides to access dienes and trienes.

Citation

Whiting, A., Madden, K. S., David, S., & Knowles, J. P. (2015). Heck-Mizoroki Coupling of Vinyliodide and Applications in The Synthesis of Dienes and Trienes. Chemical Communications, 51(57), 11409-11412. https://doi.org/10.1039/c5cc03273c

Journal Article Type	Article
Acceptance Date	Jun 10, 2015
Publication Date	Jul 21, 2015
Deposit Date	Jun 11, 2015
Publicly Available Date	Jun 10, 2016
Journal	Chemical Communications
Print ISSN	1359-7345
Electronic ISSN	1364-548X
Publisher	Royal Society of Chemistry
Peer Reviewed	Peer Reviewed
Volume	51
Issue	57
Pages	11409-11412
DOI	https://doi.org/10.1039/c5cc03273c