R.V. Ulijn
Bioresponsive hydrogels
Ulijn, R.V.; Bibi, N.; Jayawarna, V.; Thornton, P.D.; Todd, S.J.; Mart, R.J.; Smith, A.M.; Gough, J.E.
Authors
N. Bibi
V. Jayawarna
P.D. Thornton
S.J. Todd
R.J. Mart
A.M. Smith
J.E. Gough
Abstract
We highlight recent developments in hydrogel materials with biological responsiveness built in. These ‘smart’ biomaterials change properties in response to selective biological recognition events. When exposed to a biological target (nutrient, growth factor, receptor, antibody, enzyme, or whole cell), molecular recognition events trigger changes in molecular interactions that translate into macroscopic responses, such as swelling/collapse or solution-to-gel transitions. The hydrogel transitions may be used directly as optical readouts for biosensing, linked to the release of actives for drug delivery, or instigate biochemical signaling events that control or direct cellular behavior. Accordingly, bioresponsive hydrogels have gained significant interest for application in diagnostics, drug delivery, and tissue regeneration/wound healing.
Citation
Ulijn, R., Bibi, N., Jayawarna, V., Thornton, P., Todd, S., Mart, R., …Gough, J. (2007). Bioresponsive hydrogels. Materials Today, 10(4), 40-48. https://doi.org/10.1016/s1369-7021%2807%2970049-4
Journal Article Type | Article |
---|---|
Publication Date | Apr 1, 2007 |
Deposit Date | Aug 1, 2012 |
Publicly Available Date | Sep 22, 2015 |
Journal | Materials Today |
Print ISSN | 1369-7021 |
Publisher | Elsevier |
Peer Reviewed | Peer Reviewed |
Volume | 10 |
Issue | 4 |
Pages | 40-48 |
DOI | https://doi.org/10.1016/s1369-7021%2807%2970049-4 |
Files
Published Journal Article
(639 Kb)
PDF
Publisher Licence URL
http://creativecommons.org/licenses/by-nc-nd/4.0/
Copyright Statement
© Elsevier Ltd 2007 Open access under CC BY-NC-ND license. This article is published under the terms of the Creative Commons Attribution-NonCommercial-No Derivatives License (CC BY NC ND). For non-commercial purposes you may distribute and copy the article and include it in a collective work (such as an anthology), provided you do not alter or modify the article, without permission from Elsevier. The original work must always be appropriately credited. Permission is not required for this non-commercial use. For commercial use please continue to request permission via RightsLink.
Downloadable Citations
About Durham Research Online (DRO)
Administrator e-mail: dro.admin@durham.ac.uk
This application uses the following open-source libraries:
SheetJS Community Edition
Apache License Version 2.0 (http://www.apache.org/licenses/)
PDF.js
Apache License Version 2.0 (http://www.apache.org/licenses/)
Font Awesome
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
Powered by Worktribe © 2024
Advanced Search