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Small Ubiquitin-like Modifier protein SUMO enables plants to control growth independently of the phytohormone gibberellin

Conti, L.; Nelis, S.; Zhang, C.; Woodcock, A.; Swarup, R.; Galbiati, M.; Tonelli, C.; Napier, R.; Hedden, P.; Bennett, M.; Sadanandom, A.

Small Ubiquitin-like Modifier protein SUMO enables plants to control growth independently of the phytohormone gibberellin Thumbnail


Authors

L. Conti

S. Nelis

C. Zhang

A. Woodcock

R. Swarup

M. Galbiati

C. Tonelli

R. Napier

P. Hedden

M. Bennett



Abstract

Plants survive adverse conditions by modulating their growth in response to a changing environment. Gibberellins (GAs) play a key role in these adaptive responses by stimulating the degradation of growth-repressing DELLA proteins. GA binding to its receptor GID1 enables association of GID1 with DELLAs. This leads to the ubiquitin-mediated proteasomal degradation of DELLAs and consequently growth promotion. We report that DELLA-dependent growth control can be regulated independently of GA. We demonstrate that when a proportion of DELLAs is conjugated to the Small Ubiquitin-like Modifier (SUMO) protein, the extent of conjugation increases during stress. We identify a SUMO-interacting motif in GID1 and demonstrate that SUMO-conjugated DELLA binds to this motif in a GA-independent manner. The consequent sequestration of GID1 by SUMO-conjugated DELLAs leads to an accumulation of non-SUMOylated DELLAs, resulting in beneficial growth restraint during stress. We conclude that plants have developed a GA-independent mechanism to control growth.

Citation

Conti, L., Nelis, S., Zhang, C., Woodcock, A., Swarup, R., Galbiati, M., …Sadanandom, A. (2014). Small Ubiquitin-like Modifier protein SUMO enables plants to control growth independently of the phytohormone gibberellin. Developmental Cell, 28(1), 102-110. https://doi.org/10.1016/j.devcel.2013.12.004

Journal Article Type Article
Acceptance Date Dec 6, 2013
Online Publication Date Jan 13, 2014
Publication Date Jan 13, 2014
Deposit Date Sep 9, 2015
Publicly Available Date Mar 28, 2024
Journal Developmental Cell
Print ISSN 1534-5807
Electronic ISSN 1878-1551
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 28
Issue 1
Pages 102-110
DOI https://doi.org/10.1016/j.devcel.2013.12.004

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