Tuning the spontaneous formation kinetics of caffeine : malonic acid co-crystals

Nartowski, K.P.; Khimyaka, Y.Z.; Berry, D.J.

doi:10.1039/c6ce00353b

Tuning the spontaneous formation kinetics of caffeine : malonic acid co-crystals

Nartowski, K.P.; Khimyaka, Y.Z.; Berry, D.J.

Authors

K.P. Nartowski

Y.Z. Khimyaka

D.J. Berry

Abstract

It has previously been reported that the caffeine : malonic acid co-crystal system forms spontaneously upon the contact of the two materials. Here we studied the crystal growth in this system to rationally define the role that water plays, thus enabling us to monitor the conversion by solid-state NMR and control the kinetics of spontaneous co-crystal production by increasing or decreasing the relative humidity.

Citation

Nartowski, K., Khimyaka, Y., & Berry, D. (2016). Tuning the spontaneous formation kinetics of caffeine : malonic acid co-crystals. CrystEngComm, 18(15), 2617-2620. https://doi.org/10.1039/c6ce00353b

Journal Article Type	Article
Acceptance Date	Mar 15, 2016
Online Publication Date	Mar 15, 2016
Publication Date	Apr 21, 2016
Deposit Date	Apr 18, 2016
Publicly Available Date	Mar 15, 2017
Journal	CrystEngComm
Publisher	Royal Society of Chemistry
Peer Reviewed	Peer Reviewed
Volume	18
Issue	15
Pages	2617-2620
DOI	https://doi.org/10.1039/c6ce00353b