D. Kazantsev
A novel technique to incorporate structural prior information into multi-modal tomographic reconstruction
Kazantsev, D.; Ourselin, S.; Hutton, B.F.; Dobson, K.J.; Kaestner, A.P.; Lionheart, W.R.B.; Withers, P.J.; Lee, P.D.; Arridge, S.R.
Authors
S. Ourselin
B.F. Hutton
K.J. Dobson
A.P. Kaestner
W.R.B. Lionheart
P.J. Withers
P.D. Lee
S.R. Arridge
Abstract
There has been a rapid expansion of multi-modal imaging techniques in tomography. In biomedical imaging, patients are now regularly imaged using both single photon emission computed tomography (SPECT) and x-ray computed tomography (CT), or using both positron emission tomography and magnetic resonance imaging (MRI). In non-destructive testing of materials both neutron CT (NCT) and x-ray CT are widely applied to investigate the inner structure of material or track the dynamics of physical processes. The potential benefits from combining modalities has led to increased interest in iterative reconstruction algorithms that can utilize the data from more than one imaging mode simultaneously. We present a new regularization term in iterative reconstruction that enables information from one imaging modality to be used as a structural prior to improve resolution of the second modality. The regularization term is based on a modified anisotropic tensor diffusion filter, that has shape-adapted smoothing properties. By considering the underlying orientations of normal and tangential vector fields for two co-registered images, the diffusion flux is rotated and scaled adaptively to image features. The images can have different greyscale values and different spatial resolutions. The proposed approach is particularly good at isolating oriented features in images which are important for medical and materials science applications. By enhancing the edges it enables both easy identification and volume fraction measurements aiding segmentation algorithms used for quantification. The approach is tested on a standard denoising and deblurring image recovery problem, and then applied to 2D and 3D reconstruction problems; thereby highlighting the capabilities of the algorithm. Using synthetic data from SPECT co-registered with MRI, and real NCT data co-registered with x-ray CT, we show how the method can be used across a range of imaging modalities.
Citation
Kazantsev, D., Ourselin, S., Hutton, B., Dobson, K., Kaestner, A., Lionheart, W., …Arridge, S. (2014). A novel technique to incorporate structural prior information into multi-modal tomographic reconstruction. Inverse Problems, 30(6), Article 065004. https://doi.org/10.1088/0266-5611/30/6/065004
Journal Article Type | Article |
---|---|
Acceptance Date | Feb 18, 2014 |
Online Publication Date | May 19, 2014 |
Publication Date | Jun 1, 2014 |
Deposit Date | May 5, 2016 |
Publicly Available Date | May 9, 2016 |
Journal | Inverse Problems |
Print ISSN | 0266-5611 |
Electronic ISSN | 1361-6420 |
Publisher | IOP Publishing |
Peer Reviewed | Peer Reviewed |
Volume | 30 |
Issue | 6 |
Article Number | 065004 |
DOI | https://doi.org/10.1088/0266-5611/30/6/065004 |
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Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI.
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