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Do cortical plasticity mechanisms differ between males and females?

Dachtler, J. and Fox, K. (2017) 'Do cortical plasticity mechanisms differ between males and females?', Journal of neuroscience research,, 95 (1-2). pp. 518-526.


The difference between male and female behavior and male and female susceptibility to a number of neuropsychiatric conditions is not controversial. From a biological perspective, one might expect to see at least some of these differences underpinned by identifiable physical differences in the brain. This Mini-Review focuses on evidence that plasticity mechanisms differ between males and females and ask at what scale of organization the differences might exist, at the systems level, the circuits level, or the synaptic level. Emerging evidence suggests that plasticity differences may extend to the scale of synaptic mechanisms. In particular, the CaMKK, NOS1 and estrogen receptor pathways show sexual dimorphisms with implications for plasticity in the hippocampus and cerebral cortex.

Item Type:Article
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First Live Deposit - 24 November 2016
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Publisher statement:© 2016 The Authors. Journal of Neuroscience Research Published by Wiley Periodicals, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Record Created:23 Nov 2016 14:35
Last Modified:20 Feb 2017 10:25

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