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Do cortical plasticity mechanisms differ between males and females?

Dachtler, J.; Fox, K.

Do cortical plasticity mechanisms differ between males and females? Thumbnail


Authors

J. Dachtler

K. Fox



Abstract

The difference between male and female behavior and male and female susceptibility to a number of neuropsychiatric conditions is not controversial. From a biological perspective, one might expect to see at least some of these differences underpinned by identifiable physical differences in the brain. This Mini-Review focuses on evidence that plasticity mechanisms differ between males and females and ask at what scale of organization the differences might exist, at the systems level, the circuits level, or the synaptic level. Emerging evidence suggests that plasticity differences may extend to the scale of synaptic mechanisms. In particular, the CaMKK, NOS1 and estrogen receptor pathways show sexual dimorphisms with implications for plasticity in the hippocampus and cerebral cortex.

Citation

Dachtler, J., & Fox, K. (2017). Do cortical plasticity mechanisms differ between males and females?. Journal of Neuroscience Research, 95(1-2), 518-526. https://doi.org/10.1002/jnr.23850

Journal Article Type Article
Acceptance Date Jul 6, 2016
Online Publication Date Nov 7, 2016
Publication Date Jan 1, 2017
Deposit Date Nov 17, 2016
Publicly Available Date Mar 29, 2024
Journal Journal of Neuroscience Research
Print ISSN 0360-4012
Electronic ISSN 1097-4547
Publisher Wiley
Peer Reviewed Peer Reviewed
Volume 95
Issue 1-2
Pages 518-526
DOI https://doi.org/10.1002/jnr.23850

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Published Journal Article (356 Kb)
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Publisher Licence URL
http://creativecommons.org/licenses/by/4.0/

Copyright Statement
© 2016 The Authors. Journal of Neuroscience Research Published by Wiley Periodicals, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.





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