EM∩IM: Software for relating ion mobility mass spectrometry and electron microscopy data

Degiacomi, M.T.; Benesch, J.L.P.

doi:10.1039/c5an01636c

EM∩IM: Software for relating ion mobility mass spectrometry and electron microscopy data

Degiacomi, M.T.; Benesch, J.L.P.

Authors

Dr Matteo Degiacomi matteo.t.degiacomi@durham.ac.uk
Associate Professor

J.L.P. Benesch

Abstract

We present EM∩IM, software that allows the calculation of collision cross-sections from electron density maps obtained for example by means of transmission electron microscopy. This allows the assessment of structures other than those described by atomic coordinates with ion mobility mass spectrometry data, and provides a new means for contouring and validating electron density maps. EM∩IM thereby facilitates the use of data obtained in the gas phase within structural biology studies employing diverse experimental methodologies.

Citation

Degiacomi, M., & Benesch, J. (2016). EM∩IM: Software for relating ion mobility mass spectrometry and electron microscopy data. Analyst, 141(1), 70-75. https://doi.org/10.1039/c5an01636c

Journal Article Type	Article
Acceptance Date	Nov 23, 2015
Online Publication Date	Nov 23, 2015
Publication Date	Jan 7, 2016
Deposit Date	Jul 26, 2017
Publicly Available Date	Aug 8, 2017
Journal	Analyst
Print ISSN	0003-2654
Electronic ISSN	1364-5528
Publisher	Royal Society of Chemistry
Peer Reviewed	Peer Reviewed
Volume	141
Issue	1
Pages	70-75
DOI	https://doi.org/10.1039/c5an01636c