Enantioselective cellular localisation of europium(iii) coordination complexes

Frawley, Andrew T.; Linford, Holly V.; Starck, Matthieu; Pal, Robert; Parker, David

doi:10.1039/c7sc04422d

Enantioselective cellular localisation of europium(iii) coordination complexes

Frawley, Andrew T.; Linford, Holly V.; Starck, Matthieu; Pal, Robert; Parker, David

Authors

Andrew T. Frawley

Holly V. Linford

Matthieu Starck

Professor Robert Pal robert.pal@durham.ac.uk
Professor

Professor David Parker david.parker@durham.ac.uk
Emeritus Professor

Abstract

The selective mitochondrial localisation of the Λ enantiomer of three different emissive europium(III) complexes in NIH 3T3 and MCF7 cells contrasts with the behaviour of the Δ enantiomer, for which a predominant lysosomal localisation was observed by confocal microscopy. In each case, cell uptake occurs via macropinocytosis.

Citation

Frawley, A. T., Linford, H., Starck, M., Pal, R., & Parker, D. (2018). Enantioselective cellular localisation of europium(iii) coordination complexes. Chemical Science, 9(4), 1042-1049. https://doi.org/10.1039/c7sc04422d

Journal Article Type	Article
Acceptance Date	Dec 6, 2017
Online Publication Date	Dec 6, 2017
Publication Date	Jan 28, 2018
Deposit Date	Feb 8, 2018
Publicly Available Date	Feb 8, 2018
Journal	Chemical Science
Print ISSN	2041-6520
Electronic ISSN	2041-6539
Publisher	Royal Society of Chemistry
Peer Reviewed	Peer Reviewed
Volume	9
Issue	4
Pages	1042-1049
DOI	https://doi.org/10.1039/c7sc04422d