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VasoTracker, a Low-Cost and Open Source Pressure Myograph System for Vascular Physiology

Lawton, Penelope F.; Lee, Matthew D.; Saunter, Christopher D.; Girkin, John M.; McCarron, John G.; Wilson, Calum

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Authors

Matthew D. Lee

Christopher D. Saunter

John G. McCarron

Calum Wilson



Abstract

Pressure myography, one of the most commonly used techniques in vascular research, measures the diameter of isolated, pressurized arteries to assess the functional activity of smooth muscle and endothelial cells. Despite the widespread adoption of this technique for assessing vascular function, there are only a small number of commercial systems and these are expensive. Here, we introduce a complete, open source pressure myograph system and analysis software, VasoTracker, that can be set-up for approximately 10% of the cost of commercial alternatives. We report on the development of VasoTracker and demonstrate its ability to assess various components of vascular reactivity. A unique feature of the VasoTracker platform is the publicly accessible website (http://www.vasotracker.com/) that documents how to assemble and use this affordable, adaptable, and expandable pressure myograph.

Citation

Lawton, P. F., Lee, M. D., Saunter, C. D., Girkin, J. M., McCarron, J. G., & Wilson, C. (2019). VasoTracker, a Low-Cost and Open Source Pressure Myograph System for Vascular Physiology. Frontiers in Physiology, 10, Article 99. https://doi.org/10.3389/fphys.2019.00099

Journal Article Type Article
Acceptance Date Jan 28, 2019
Online Publication Date Feb 21, 2019
Publication Date Feb 21, 2019
Deposit Date Feb 21, 2019
Publicly Available Date Feb 21, 2019
Journal Frontiers in Physiology
Publisher Frontiers Media
Peer Reviewed Peer Reviewed
Volume 10
Article Number 99
DOI https://doi.org/10.3389/fphys.2019.00099

Files

Published Journal Article (7 Mb)
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Publisher Licence URL
http://creativecommons.org/licenses/by/4.0/

Copyright Statement
Copyright © 2019 Lawton, Lee, Saunter, Girkin, McCarron and Wilson. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.





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