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A simple solid phase diversity linker strategy using enol phosphonates.

Campbell, I. B. and Guo, J. and Jones, E. and Steel, P. G. (2004) 'A simple solid phase diversity linker strategy using enol phosphonates.', Organic & biomolecular chemistry., 2 (19). pp. 2725-2727.


Polymer bound lactam enol phosphonates can be easily generated using simple phenol on polystyrene resin. These stable, storable compounds can be released in a diversity cleavage strategy, using Suzuki cross coupling conditions, to provide 2-arylenamides in moderate to good overall yields.

Item Type:Article
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Record Created:19 Apr 2007
Last Modified:08 Apr 2009 16:30

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