Dyer, P. W. and Fawcett, J. and Griffith, G. A. and Hanton, M. J. and Olivier, C. and Patterson, A. R. and Suhard, S. (2005) 'Sterically-controlled regioselective para-substitutions of aniline.', Chemical communications. (30). pp. 3835-3837.
Introduction of sterically demanding 1-isopropyl-2-methyl-propyl or triisopropylsilyl groups at the nitrogen of aniline allows high-yielding regioselective para-substitution to be achieved using a lithiation/substitution sequence.
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|Publisher Web site:||http://dx.doi.org/10.1039/b506824j|
|Record Created:||10 May 2007|
|Last Modified:||08 Apr 2009 16:31|
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