Baron, A. and Sandford, G. and Slater, R. and Yufit, D. S. and Howard, J. A. K. and Vong, A. (2005) 'Polyfunctional tetrahydropyrido[2,3-b]pyrazine scaffolds from 4-phenylsulfonyl tetrafluoropyridine.', Journal of organic chemistry., 70 (23). pp. 9377-9381.
Polyfunctional tetrahydropyrido[2,3-b]pyrazine scaffolds can be synthesized by sequential reaction of pentafluoropyridine with sodium phenylsulfinate and an appropriate diamine. The polyfunctionality possessed by the difluorinated tetrahydropyrido[2,3-b]pyrazine scaffolds was demonstrated in selected model reactions with nucleophiles to give access to various polysubstituted [6,6]-ring fused systems.
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|Publisher Web site:||http://dx.doi.org/10.1021/jo051453v|
|Record Created:||11 May 2007|
|Last Modified:||08 Apr 2009 16:31|
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