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fMRI and cognitive dysfunction in schizophrenia

Mitchell, R.; Elliott, R.; Woodruff, P.W.R.

Authors

R. Mitchell

R. Elliott

P.W.R. Woodruff



Abstract

Despite being one of the most prevalent psychiatric conditions, SCHIZOPHRENIA is still poorly understood, with no clear objective biological marker. The advent of neuroimaging has enabled in vivo investigations to complement older techniques, and has revealed important insights. fMRI provides a means to assess the neurobiological theory that schizophrenia is caused by abnormal fronto-temporal lobe connections. In studies of language abnormalities, fMRI can explicitly assess the hypothesis that the normal lateralization of language is reversed in schizophrenia. Longitudinal fMRI studies, and studies examining the effects of medication, suggest that the technique has further potential to advance our understanding of this complex disorder.

Citation

Mitchell, R., Elliott, R., & Woodruff, P. (2001). fMRI and cognitive dysfunction in schizophrenia. Trends in Cognitive Sciences, 5(2), 71-80. https://doi.org/10.1016/s1364-6613%2800%2901599-0

Journal Article Type Article
Publication Date Feb 1, 2001
Deposit Date Jan 8, 2008
Journal Trends in Cognitive Sciences
Print ISSN 1364-6613
Publisher Cell Press
Peer Reviewed Peer Reviewed
Volume 5
Issue 2
Pages 71-80
DOI https://doi.org/10.1016/s1364-6613%2800%2901599-0
Keywords Neuroimaging, Lateralization, Schizophrenia, Psychopathology, Fronto-temporal.