The role of V5/MT+ in the control of catching movements: an rTMS study

Abstract

Milner and Goodale [Milner, A. D., & Goodale, M. A. (1995). The visual brain in action. Oxford: Oxford University Press] described a model which distinguishes between two visual streams in the brain. It is claimed that the ventral stream serves object recognition (i.e. vision for perception), and the dorsal streams provides visual information for the guidance of action (i.e. vision for action). This model is supported by evidence from the domain of spatial vision, but it remains unclear how motion vision fits into that model. More specifically, it is unclear how the motion complex V5/MT contributes to vision for perception and vision for action. We addressed this question in an earlier study with the V5-lesioned patient LM [Schenk, T., Mai, N., Ditterich, J., & Zihl, J. (2000). Can a motion-blind patient reach for moving objects? European Journal of Neuroscience, 12, 3351–3360]. We found that she is not only impaired in perceptual tasks but also in catching, suggesting a role for V5/MT+ in vision for both perception and action. However, LM's lesion goes beyond V5/MT+ into more dorsal regions. It is thus possible, that the catching deficit was not produced by damage to V5/MT+ itself. In this case, one would expect that selective interference with V5/MT+ would have no effect on catching. In the present study we tested this prediction by applying rTMS over V5/MT+ of the left hemisphere while healthy subjects were either performing a catching or a reaching task. We found that V5-TMS reduced the speed of the catching but not the reaching response. These results confirm that V5/MT+ is not only involved in perceptual but also in visuomotor tasks.