Hormonal control of metabolism: regulation of plasma glucose

Yeo, R.P.; Sawdon, M.

doi:10.1016/j.mpaic.2010.04.001

Hormonal control of metabolism: regulation of plasma glucose

Yeo, R.P.; Sawdon, M.

Authors

R.P. Yeo

M. Sawdon

Abstract

The control of plasma glucose needs to be tightly monitored because hyperglycaemia and hypoglycaemia can lead to severe clinical problems, including death. In this article the major mechanism for the transport of glucose into and out of the blood and how that mechanism is used to monitor the circulating concentrations of glucose are discussed. A number of hormones regulate glucose in response to changes in plasma concentrations. Insulin promotes the removal of glucose and its conversion to glycogen. Glucagon, in response to falling glucose concentrations, increases the breakdown of glycogen and the release of glucose from the liver. There are many other hormones that play a part in assisting the functions of insulin and glucagon. Failures in the appropriate production of such hormones may lead to the unregulated changes in plasma glucose and subsequent health problems.

Citation

Yeo, R., & Sawdon, M. (2010). Hormonal control of metabolism: regulation of plasma glucose. Anaesthesia and intensive care medicine, 11(7), 279-283. https://doi.org/10.1016/j.mpaic.2010.04.001

Journal Article Type	Article
Publication Date	Jul 1, 2010
Deposit Date	Aug 3, 2010
Publicly Available Date	Aug 10, 2010
Journal	Anaesthesia and intensive care medicine.
Print ISSN	1472-0299
Publisher	Elsevier
Peer Reviewed	Peer Reviewed
Volume	11
Issue	7
Pages	279-283
DOI	https://doi.org/10.1016/j.mpaic.2010.04.001
Keywords	Glucose, Homeostasis, Hormonal regulation, Plasma.