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The synthesis of peptides and proteins containing non-natural amino acids.

Hodgson, D. R. W. and Sanderson, J. M. (2004) 'The synthesis of peptides and proteins containing non-natural amino acids.', Chemical society reviews., 33 (7). pp. 422-430.

Abstract

Methods for the incorporation of non-natural amino acids into proteins have advanced significantly over recent years and in this tutorial review we aim to give a general overview of the area. These techniques offer the possibility of modulating the structures and functions of proteins and thus permit the generation of novel designed systems for both biocatalytic and mechanistic studies. Four complementary approaches are discussed in detail along with examples of their application. The advantages and disadvantages of each technique are also discussed.

Item Type:Article
Full text:Full text not available from this repository.
Publisher Web site:http://dx.doi.org/10.1039/b312953p
Record Created:21 Jun 2011 15:05
Last Modified:03 Jan 2012 15:06

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