A Ruigómez
Treatment patterns in paediatric patients with a new diagnosis of gastroesophageal reflux disease
Ruigómez, A; Hungin, AP; Lundborg, P; Johansson, S; Wallander, MA; Garcia Rodríguez, LA
Authors
AP Hungin
P Lundborg
S Johansson
MA Wallander
LA Garcia Rodríguez
Abstract
Objective: Few data exist on the treatment of gastroesophageal reflux disease (GERD) in paediatrics. The objective of this study was to examine treatment patterns of GERD in paediatrics in the primary care. Methods: Incident GERD cases among paediatric patientswere identified using The Health Improvement Network UK primary care database. We assessed prescription treatments in 30 days before and any time after the date of diagnosis. Initial treatment was defined asthat received in 30 days either side of diagnosis. Odds ratios and 95% confidence intervals of receiving the treatment were calculated by multiple logistic regressions. Results: The incident GERD cohort comprised 1700 paediatric patients aged 1–17 years. Antacids were initiallyprescribed in 49.2% of patients. Similar proportions of patients (23.3 and 22.9%) received histamine-2 receptor antagonists (H2RAs) and proton pump inhibitors (PPIs); 7.5% were prescribed prokinetics and 19.3% received no prescribed treatment. Overall, 24.7% of initial H2RA users switched to PPIs, and 9.8% of those using PPIs switched toH2RAs. The likelihood of the use of PPI increased with age and was lower in girls than in boys (odds ratio: 0.7; 95% confidence interval: 0.5–0.9). Conclusions: Antacids are the drugs most frequently prescribed by primary care physicians to paediatric patients with GERD, and approximately half receive an initial course of antisecretory treatment with H2RAs or PPIs. This study suggests that treatment patterns in paediatrics differ from those in adults.
Citation
Ruigómez, A., Hungin, A., Lundborg, P., Johansson, S., Wallander, M., & Garcia Rodríguez, L. (2011). Treatment patterns in paediatric patients with a new diagnosis of gastroesophageal reflux disease. European Journal of Gastroenterology & Hepatology, 23(3), 232-237. https://doi.org/10.1097/meg.0b013e328343b06e
Journal Article Type | Article |
---|---|
Publication Date | Mar 1, 2011 |
Deposit Date | Jul 11, 2011 |
Journal | European Journal of Gastroenterology and Hepatology |
Print ISSN | 0954-691X |
Electronic ISSN | 1473-5687 |
Publisher | Lippincott, Williams & Wilkins |
Peer Reviewed | Peer Reviewed |
Volume | 23 |
Issue | 3 |
Pages | 232-237 |
DOI | https://doi.org/10.1097/meg.0b013e328343b06e |
You might also like
Transition from childhood to adulthood in coeliac disease: the Prague consensus report
(2016)
Journal Article
What calprotectin cut-offs should apply for IBD in general practice?
(2016)
Journal Article
Faecal biomarker patterns in patients with symptoms of irritable bowel syndrome
(2016)
Journal Article
Downloadable Citations
About Durham Research Online (DRO)
Administrator e-mail: dro.admin@durham.ac.uk
This application uses the following open-source libraries:
SheetJS Community Edition
Apache License Version 2.0 (http://www.apache.org/licenses/)
PDF.js
Apache License Version 2.0 (http://www.apache.org/licenses/)
Font Awesome
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
Powered by Worktribe © 2024
Advanced Search