A.P.S. Hungin
Nonsteroidal anti-inflammatory drugs: Overused or underused in osteoarthritis?
Hungin, A.P.S.; Kean, W.
Authors
W. Kean
Contributors
Lee Goldman
Editor
Abstract
Arthritis and musculoskeletal disorders are common. Arthritis currently accounts for 2% to 3% of all cases of disability, and the numbers are rising. Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used, with 75 million prescriptions annually in the United States and 25 million in the United Kingdom. The volume of side effects noted, most of which are gastrointestinal and can be serious, imply the overuse of these drugs, especially in relation to the estimated prevalence of osteoarthritis (OA), where pain relief may be considered more important than an anti-inflammatory effect. There are conflicting data about the efficacy of NSAIDs compared with analgesics alone for pain relief. However, the interpretation of data comparing the two drug classes is limited by shortcomings in research methodologies and by difficulties in incorporating the anti-inflammatory effect of NSAIDs into the outcomes. The efficacy of paracetamol for some patients has been underestimated; however, although those with mild disease may find paracetamol adequate, most patients with OA are likely to gain more benefit from NSAIDs.
Citation
Hungin, A., & Kean, W. (2001). Nonsteroidal anti-inflammatory drugs: Overused or underused in osteoarthritis?. American Journal of Medicine, 110(1A), 8S-11S. https://doi.org/10.1016/s0002-9343%2800%2900628-8
Journal Article Type | Article |
---|---|
Publication Date | Jan 8, 2001 |
Deposit Date | Jun 14, 2012 |
Journal | American journal of medicine. |
Print ISSN | 0002-9343 |
Publisher | Elsevier |
Peer Reviewed | Peer Reviewed |
Volume | 110 |
Issue | 1A |
Pages | 8S-11S |
DOI | https://doi.org/10.1016/s0002-9343%2800%2900628-8 |
You might also like
Transition from childhood to adulthood in coeliac disease: the Prague consensus report
(2016)
Journal Article
What calprotectin cut-offs should apply for IBD in general practice?
(2016)
Journal Article
Faecal biomarker patterns in patients with symptoms of irritable bowel syndrome
(2016)
Journal Article
Downloadable Citations
About Durham Research Online (DRO)
Administrator e-mail: dro.admin@durham.ac.uk
This application uses the following open-source libraries:
SheetJS Community Edition
Apache License Version 2.0 (http://www.apache.org/licenses/)
PDF.js
Apache License Version 2.0 (http://www.apache.org/licenses/)
Font Awesome
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
Powered by Worktribe © 2024
Advanced Search