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Rational drug design - identifying and characterising a target.

Todd, A. and Anderson, R.J. and Groundwater, P.W. (2009) 'Rational drug design - identifying and characterising a target.', The pharmaceutical journal., 283 (7559). pp. 19-20.


Structure-based drug design is now a common method used by the pharmaceutical industry to identify a lead compound and take it forward for further development. This article describes the methods used to identify and characterise a target for structured drug design and illustrates how pharmacists can play an important role in this process, under the headings: identifying a target; proteomics; the poptein databank; DNA; enzyme inhibitors; receptor agonists and antagonists; rational drug design.

Item Type:Article
Keywords:Drug Development, Structure-activity Relationship, Proteins, DNA, Enzyme Inhibitors, Review.
Full text:Full text not available from this repository.
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Record Created:28 Jun 2012 11:20
Last Modified:05 Dec 2012 12:33

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