A Todd
Rational drug design — identifying and characterising a target
Todd, A; Anderson, R.J; Groundwater, P.W
Authors
R.J Anderson
P.W Groundwater
Abstract
Structure-based drug design is now a common method used by the pharmaceutical industry to identify a lead compound and take it forward for further development. This article describes the methods used to identify and characterise a target for structured drug design and illustrates how pharmacists can play an important role in this process, under the headings: identifying a target; proteomics; the poptein databank; DNA; enzyme inhibitors; receptor agonists and antagonists; rational drug design.
Citation
Todd, A., Anderson, R., & Groundwater, P. (2009). Rational drug design — identifying and characterising a target. Pharmaceutical journal (1933), 283(7559), 19-20
Journal Article Type | Article |
---|---|
Publication Date | Jul 1, 2009 |
Deposit Date | Jun 19, 2012 |
Journal | Pharmaceutical Journal |
Print ISSN | 0031-6873 |
Publisher | Royal Pharmaceutical Society of Great Britain |
Peer Reviewed | Peer Reviewed |
Volume | 283 |
Issue | 7559 |
Pages | 19-20 |
Keywords | Drug Development, Structure-activity Relationship, Proteins, DNA, Enzyme Inhibitors, Review. |
Publisher URL | http://www.pjonline.com/contents/pj20090704 |
You might also like
The Role of Patient Preferences in Deprescribing
(2017)
Journal Article
Safety profile of lamotrigine in overdose
(2016)
Journal Article
Downloadable Citations
About Durham Research Online (DRO)
Administrator e-mail: dro.admin@durham.ac.uk
This application uses the following open-source libraries:
SheetJS Community Edition
Apache License Version 2.0 (http://www.apache.org/licenses/)
PDF.js
Apache License Version 2.0 (http://www.apache.org/licenses/)
Font Awesome
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
Powered by Worktribe © 2024
Advanced Search