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The impact of insecticide-treated school uniforms on dengue infections in school-aged children: study protocol for a randomised controlled trial in Thailand

Wilder-Smith, A.; Byass, P.; Olanratmanee, P.; Maskhao, P.; Sringernyuang, L.; Logan, J.G.; Lindsay, S.W.; Banks, S.; Gubler, D.; Louis, V.R.; Tozan, Y.; Kittayapong, P.

The impact of insecticide-treated school uniforms on dengue infections in school-aged children: study protocol for a randomised controlled trial in Thailand Thumbnail


Authors

A. Wilder-Smith

P. Byass

P. Olanratmanee

P. Maskhao

L. Sringernyuang

J.G. Logan

S. Banks

D. Gubler

V.R. Louis

Y. Tozan

P. Kittayapong



Abstract

Background: There is an urgent need to protect children against dengue since this age group is particularly sensitive to the disease. Since dengue vectors are active mainly during the day, a potential target for control should be schools where children spend a considerable amount of their day. School uniforms are the cultural norm in most developing countries, worn throughout the day. We hypothesise that insecticide-treated school uniforms will reduce the incidence of dengue infection in school-aged children. Our objective is to determine the impact of impregnated school uniforms on dengue incidence. Methods: A randomised controlled trial will be conducted in eastern Thailand in a group of schools with approximately 2,000 students aged 7–18 years. Pre-fabricated school uniforms will be commercially treated to ensure consistent, high-quality insecticide impregnation with permethrin. A double-blind, randomised, crossover trial at the school level will cover two dengue transmission seasons. Discussion: Practical issues and plans concerning intervention implementation, evaluation, analysing and interpreting the data, and possible policy implications arising from the trial are discussed. Trial registration: clinicaltrial.gov. Registration number: NCT01563640.

Citation

Wilder-Smith, A., Byass, P., Olanratmanee, P., Maskhao, P., Sringernyuang, L., Logan, J., …Kittayapong, P. (2012). The impact of insecticide-treated school uniforms on dengue infections in school-aged children: study protocol for a randomised controlled trial in Thailand. Trials, 13(11), Article 212. https://doi.org/10.1186/1745-6215-13-212

Journal Article Type Article
Publication Date Nov 15, 2012
Deposit Date Apr 10, 2013
Publicly Available Date Mar 28, 2024
Journal Trials
Publisher BioMed Central
Peer Reviewed Peer Reviewed
Volume 13
Issue 11
Article Number 212
DOI https://doi.org/10.1186/1745-6215-13-212
Keywords Dengue, Insecticide-treated clothes, School children, School uniforms, Randomised control trial, Cost effectiveness.

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Copyright Statement
© 2012 Wilder-Smith et al.; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.





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