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EuroTracker dyes : highly emissive europium complexes as alternative organelle stains for live cell imaging.

Butler, Stephen J. and Lamarque, Laurent and Pal, Robert and Parker, David (2014) 'EuroTracker dyes : highly emissive europium complexes as alternative organelle stains for live cell imaging.', Chemical science., 2014 (5). pp. 1750-1756.

Abstract

Nine very bright europium(III) complexes with different macrocyclic ligands have been prepared that exhibit excellent cell uptake behaviour and distinctive sub-cellular localisation profiles, allowing the use of fluorescence microscopy and time-gated spectral imaging to track their fate in cellulo. Their use as cellular imaging stains is described for the selective illumination of mitochondria, lysosomes or the endoplasmic reticulum of various mammalian cell types.

Item Type:Article
Full text:(AM) Accepted Manuscript
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Status:Peer-reviewed
Publisher Web site:http://dx.doi.org/10.1039/C3SC53056F
Date accepted:11 December 2013
Date deposited:18 June 2014
Date of first online publication:27 January 2014
Date first made open access:11 December 2014

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