Bonetti, Daniel and Delbem, Alexandre and Einbeck, Jochen (2014) 'Bivariate estimation of distribution algorithms for protein structure prediction.', in 29th International Workshop on Statistical Modelling, 14-18 July 2014, Göttingen, Germany ; proceedings. Amsterdam: Statistical Modelling Society, pp. 15-18.
A real-valued bivariate ‘Estimation of Distribution Algorithm’ specific for the ab initio and full-atom Protein Structure Prediction problem is proposed. It is known that this is a multidimensional and multimodal problem. In order to deal with the multimodality and the correlation of dihedral angles φ and ψ, we developed approaches based on Kernel Density Estimation and Finite Gaussian Mixtures. Simulation results have shown that both techniques are promising when applied to that problem.
|Item Type:||Book chapter|
|Full text:||(AM) Accepted Manuscript|
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|Publisher Web site:||http://www.statmod.org/workshops_archive_proceedings_2014.htm|
|Date accepted:||No date available|
|Date deposited:||06 October 2014|
|Date of first online publication:||2014|
|Date first made open access:||No date available|
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