H.J. Korhonen
A procedure for the preparation and isolation of nucleoside-5’-diphosphates
Korhonen, H.J.; Bolt, H.L.; Hodgson, D.R.W.
Abstract
Tris[bis(triphenylphosphoranylidene)ammonium] pyrophosphate (PPN pyrophosphate) was used in the SN2 displacements of the tosylate ion from 5’-tosylnucleosides to afford nucleoside-5’-diphosphates. Selective precipitation permitted the direct isolation of nucleoside-5’-diphosphates from crude reaction mixtures.
Citation
Korhonen, H., Bolt, H., & Hodgson, D. (2015). A procedure for the preparation and isolation of nucleoside-5’-diphosphates. Beilstein Journal of Organic Chemistry, 11, 469-472. https://doi.org/10.3762/bjoc.11.52
Journal Article Type | Article |
---|---|
Acceptance Date | Mar 25, 2015 |
Publication Date | Apr 10, 2015 |
Deposit Date | Apr 8, 2015 |
Publicly Available Date | Mar 29, 2024 |
Journal | Beilstein Journal of Organic Chemistry |
Print ISSN | 1860-5397 |
Publisher | Beilstein-Institut |
Peer Reviewed | Peer Reviewed |
Volume | 11 |
Pages | 469-472 |
DOI | https://doi.org/10.3762/bjoc.11.52 |
Keywords | NDP synthesis, Nucleic acids, Nucleoside-5’-diphosphate, Phosphorylation. |
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Copyright Statement
© 2015 Korhonen et al; licensee Beilstein-Institut.
This is an Open Access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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