Moving beyond standard procedures to assess spontaneous recognition memory

Ameen-Ali, K.E.; Easton, A.; Eacott, M.J.

doi:10.1016/j.neubiorev.2015.03.013

Moving beyond standard procedures to assess spontaneous recognition memory

Ameen-Ali, K.E.; Easton, A.; Eacott, M.J.

Authors

K.E. Ameen-Ali

Professor Alex Easton alexander.easton@durham.ac.uk
Professor

M.J. Eacott

Abstract

This review will consider how spontaneous tasks have been applied alongside neuroscientific techniques to test complex forms of recognition memory for objects and their environmental features, e.g. the spatial location of an object or the context in which it is presented. We discuss studies that investigate the roles of the perirhinal cortex and the hippocampus in recognition memory using standard testing paradigms, and consider how these findings contribute to the ongoing debate about whether recognition memory is a single unitary process or multiple processes that can be dissociated anatomically and functionally. Due to the wide use of spontaneous tasks, the need for improved procedures that reduce animal use is acknowledged, with multiple trial paradigms discussed as a novel way of reducing variability and animal numbers in these tasks. The importance of improving translation of animal models to humans is highlighted, with emphasis on a shift away from relying on the phenomenological experience of human subjects.

Citation

Ameen-Ali, K., Easton, A., & Eacott, M. (2015). Moving beyond standard procedures to assess spontaneous recognition memory. Neuroscience & Biobehavioral Reviews, 53, 37-51. https://doi.org/10.1016/j.neubiorev.2015.03.013

Journal Article Type	Article
Acceptance Date	Mar 25, 2015
Publication Date	Jun 1, 2015
Deposit Date	Mar 25, 2015
Publicly Available Date	Apr 15, 2015
Journal	Neuroscience and Biobehavioral Reviews
Print ISSN	0149-7634
Publisher	Elsevier
Peer Reviewed	Peer Reviewed
Volume	53
Pages	37-51
DOI	https://doi.org/10.1016/j.neubiorev.2015.03.013
Keywords	Recognition memory, Episodic memory, Perirhinal cortex, Hippocampus, Novelty, Familiarity.

Files

Published Journal Article (2.4 Mb)
PDF

Publisher Licence URL
http://creativecommons.org/licenses/by/4.0/

Copyright Statement
© 2015 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license
(http://creativecommons.org/licenses/by/4.0/).