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Design and Optimisation of a Microgripper: Demonstration of Biomedical Applications Using the Manipulation of Oocytes

Solano, B.P.; Gallant, A.J.; Wood, D.

Authors

B.P. Solano

D. Wood



Contributors

T. Bourouina
Editor

B. Courtois
Editor

R. Ghodssi
Editor

A. Soma
Editor

H. Yang
Editor

J. M. Karam
Editor

Abstract

We present a bidirectional electrothermal microgripper for the advanced manipulation of single large cells. The device demonstrates excellent performance, and shows great potential as a supporting microtool for different biomedical procedures such as oocyte selection or electrofusion of cells. In particular, we focus on the operation of the device in real environments, i.e. integrated in a standard biological micromanipulation station and entirely submerged in a biological fluid, for the handling and transportation of ‘live’ specimens (in our case mice oocytes). A clamping mechanism is included in the design that limits the pressure exerted over the biological specimen to an approximate maximum of 40 μN, whilst maintaining a robust grip, with a force up to 300 μN, between the arms of the microgripper.

Citation

Solano, B., Gallant, A., & Wood, D. (2009). Design and Optimisation of a Microgripper: Demonstration of Biomedical Applications Using the Manipulation of Oocytes. In T. Bourouina, B. Courtois, R. Ghodssi, A. Soma, H. Yang, & J. M. Karam (Eds.), Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS (DTIP), Rome, Italy, 1-3 April 2009 (61-65)

Conference Name DTIP 2009: SYMPOSIUM ON DESIGN, TEST, INTEGRATION AND PACKAGING OF MEMS/MOEMS
Conference Location Rome, Italy
Online Publication Date May 12, 2009
Publication Date May 12, 2009
Deposit Date Oct 1, 2010
Publisher Institute of Electrical and Electronics Engineers
Pages 61-65
Book Title Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS (DTIP), Rome, Italy, 1-3 April 2009.
Keywords Microgripper, Electrothermal
Public URL https://durham-repository.worktribe.com/output/1158661
Publisher URL http://ieeexplore.ieee.org/document/4919504/


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