Solano, B.P. and Gallant, A.J. and Wood, D. (2009) 'Design and optimisation of a microgripper : demonstration of biomedical applications using the manipulation of oocytes.', in Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS (DTIP), Rome, Italy, 1-3 April 2009. Piscataway, NJ: IEEE, pp. 61-65.
We present a bidirectional electrothermal microgripper for the advanced manipulation of single large cells. The device demonstrates excellent performance, and shows great potential as a supporting microtool for different biomedical procedures such as oocyte selection or electrofusion of cells. In particular, we focus on the operation of the device in real environments, i.e. integrated in a standard biological micromanipulation station and entirely submerged in a biological fluid, for the handling and transportation of ‘live’ specimens (in our case mice oocytes). A clamping mechanism is included in the design that limits the pressure exerted over the biological specimen to an approximate maximum of 40 μN, whilst maintaining a robust grip, with a force up to 300 μN, between the arms of the microgripper.
|Item Type:||Book chapter|
|Full text:||Publisher-imposed embargo |
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|Publisher Web site:||http://ieeexplore.ieee.org/document/4919504/|
|Date accepted:||No date available|
|Date deposited:||30 April 2015|
|Date of first online publication:||12 May 2009|
|Date first made open access:||No date available|
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