Ethyl 2-hydroxy-2-phenyl-2-(thiazol-2-yl)acetate

Mallia, C.J.; Englert, L.; Walter, G.C.; Baxendale, I.R.

doi:10.3390/m857

Ethyl 2-hydroxy-2-phenyl-2-(thiazol-2-yl)acetate

Mallia, C.J.; Englert, L.; Walter, G.C.; Baxendale, I.R.

Authors

C.J. Mallia

L. Englert

G.C. Walter

Professor Ian Baxendale i.r.baxendale@durham.ac.uk
Professor

Abstract

This short note describes the synthesis of the title compound through spontaneous aerobic oxidation of ethyl 2-phenyl-2-(thiazol-2-yl)acetate. Due to the prevalence of such functional motifs in biologically active substances, we believe the oxidation encountered highlights an important degradation pathway worthy of note.

Citation

Mallia, C., Englert, L., Walter, G., & Baxendale, I. (2015). Ethyl 2-hydroxy-2-phenyl-2-(thiazol-2-yl)acetate. Molbank, 2015(2), https://doi.org/10.3390/m857

Journal Article Type	Article
Acceptance Date	May 4, 2015
Publication Date	May 6, 2015
Deposit Date	May 4, 2015
Publicly Available Date	Jun 1, 2015
Journal	Molbank
Publisher	MDPI
Peer Reviewed	Peer Reviewed
Volume	2015
Issue	2
DOI	https://doi.org/10.3390/m857
Keywords	Thiazole, Oxidation product, Heterocycles.

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© 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license
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