Continuous flow based catch and release protocol for the synthesis of alpha-ketoesters

Palmieri, Alessandro; Ley, Steven V.; Polyzos, Anastasios; Ladlow, Mark; Baxendale, Ian R.

doi:10.3762/bjoc.5.23

Continuous flow based catch and release protocol for the synthesis of alpha-ketoesters

Palmieri, Alessandro; Ley, Steven V.; Polyzos, Anastasios; Ladlow, Mark; Baxendale, Ian R.

Authors

Alessandro Palmieri

Steven V. Ley

Anastasios Polyzos

Mark Ladlow

Professor Ian Baxendale i.r.baxendale@durham.ac.uk
Professor

Abstract

Using a combination of commercially available mesofluidic flow equipment and tubes packed with immobilised reagents and scavengers, a new synthesis of α-ketoesters is reported.

Citation

Palmieri, A., Ley, S. V., Polyzos, A., Ladlow, M., & Baxendale, I. R. (2009). Continuous flow based catch and release protocol for the synthesis of alpha-ketoesters. Beilstein Journal of Organic Chemistry, 5, Article 23. https://doi.org/10.3762/bjoc.5.23

Journal Article Type	Article
Acceptance Date	May 14, 2009
Publication Date	May 20, 2009
Deposit Date	Jul 14, 2014
Publicly Available Date	Jun 1, 2015
Journal	Beilstein Journal of Organic Chemistry
Print ISSN	1860-5397
Publisher	Beilstein-Institut
Peer Reviewed	Peer Reviewed
Volume	5
Article Number	23
DOI	https://doi.org/10.3762/bjoc.5.23
Keywords	Catch and release, Flow synthesis, α-ketoesters, Mesoreactor, Polymer supported reagents.

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Copyright Statement
© 2009 Baumann et al; licensee Beilstein-Institut. This is an Open Access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (http://www.beilstein-journals.org/bjoc)