Exploring Flow Procedures for Diazonium Formation

Hu, T.; Baxendale, I.R.; Baumann, M.

doi:10.3390/molecules21070918

Exploring Flow Procedures for Diazonium Formation

Hu, T.; Baxendale, I.R.; Baumann, M.

Authors

T. Hu

Professor Ian Baxendale i.r.baxendale@durham.ac.uk
Professor

M. Baumann

Abstract

The synthesis of diazonium salts is historically an important transformation extensively utilized in dye manufacture. However the highly reactive nature of the diazonium functionality has additionally led to the development of many new reactions including several carbon-carbon bond forming processes. It is therefore highly desirable to determine optimum conditions for the formation of diazonium compounds utilizing the latest processing tools such as flow chemistry to take advantage of the increased safety and continuous manufacturing capabilities. Herein we report a series of flow-based procedures to prepare diazonium salts for subsequent in-situ consumption.

Citation

Hu, T., Baxendale, I., & Baumann, M. (2016). Exploring Flow Procedures for Diazonium Formation. Molecules, 21(7), Article 918. https://doi.org/10.3390/molecules21070918

Journal Article Type	Article
Acceptance Date	Jul 5, 2016
Online Publication Date	Jul 14, 2016
Publication Date	Jul 14, 2016
Deposit Date	Jul 14, 2016
Publicly Available Date	Jul 20, 2016
Journal	Molecules
Publisher	MDPI
Peer Reviewed	Peer Reviewed
Volume	21
Issue	7
Article Number	918
DOI	https://doi.org/10.3390/molecules21070918

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© 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).