Bose, Shubhankar K. and Deißenberger, Andrea and Eichhorn, Antonius and Steel, Patrick G. and Lin, Zhenyang and Marder, Todd B. (2015) 'Zinc-catalyzed dual C–X and C–H borylation of aryl halides.', Angewandte chemie international edition., 54 (40). pp. 11843-11847.
A zinc-catalyzed combined C[BOND]X and C[BOND]H borylation of aryl halides using B2pin2 (pin=OCMe2CMe2O) to produce the corresponding 1,2-diborylarenes under mild conditions was developed. Catalytic C[BOND]H bond activation occurs ortho to the halide groups if such a site is available or meta to the halide if the ortho position is already substituted. This method thus represents a novel use of a group XII catalyst for C[BOND]H borylation. This transformation does not proceed via a free aryne intermediate, but a radical process seems to be involved.
|Full text:||(AM) Accepted Manuscript|
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|Publisher Web site:||https://doi.org/10.1002/anie.201505603|
|Publisher statement:||This is the peer reviewed version of the following article: Bose, Shubhankar K., Deißenberger, Andrea, Eichhorn, Antonius, Steel, Patrick G., Lin, Zhenyang & Marder, Todd B. (2015). Zinc-Catalyzed Dual C–X and C–H Borylation of Aryl Halides. Angewandte Chemie International Edition 54(40): 11843-11847, which has been published in final form at https://doi.org/10.1002/anie.201505603. This article may be used for non-commercial purposes in accordance With Wiley-VCH Terms and Conditions for self-archiving.|
|Date accepted:||17 June 2015|
|Date deposited:||13 March 2017|
|Date of first online publication:||18 August 2015|
|Date first made open access:||No date available|
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