High Pressure/Low Temperature Polymorphism in 2,6-Dimethylpyridine–Formic Acid Cocrystals

Lee, Rachael; Yufit, Dmitry S.; Probert, Michael R.; Steed, Jonathan W.

doi:10.1021/acs.cgd.6b01656

High Pressure/Low Temperature Polymorphism in 2,6-Dimethylpyridine–Formic Acid Cocrystals

Lee, Rachael; Yufit, Dmitry S.; Probert, Michael R.; Steed, Jonathan W.

Authors

Rachael Lee

Dmitry S. Yufit

Michael R. Probert

Professor Jonathan Steed jon.steed@durham.ac.uk
Professor

Abstract

Five new cocrystals of 2,6-dimethylpyridine (DMP) with formic acid (FA) were crystallized by application of pressure in a diamond anvil cell and by in situ cryo-crystallization. Mixtures in ratios 1:1, 1:2, and 1:3 of DMP–FA have crystallized via both methods. Both the 1:2 and 1:3 cocrystals exhibit high pressure/low temperature polymorphism.

Citation

Lee, R., Yufit, D. S., Probert, M. R., & Steed, J. W. (2017). High Pressure/Low Temperature Polymorphism in 2,6-Dimethylpyridine–Formic Acid Cocrystals. Crystal Growth and Design, 17(4), 1647-1653. https://doi.org/10.1021/acs.cgd.6b01656

Journal Article Type	Article
Acceptance Date	Feb 28, 2017
Online Publication Date	Mar 1, 2017
Publication Date	Apr 15, 2017
Deposit Date	Apr 27, 2017
Publicly Available Date	Mar 1, 2018
Journal	Crystal Growth and Design
Print ISSN	1528-7483
Electronic ISSN	1528-7505
Publisher	American Chemical Society
Peer Reviewed	Peer Reviewed
Volume	17
Issue	4
Pages	1647-1653
DOI	https://doi.org/10.1021/acs.cgd.6b01656

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Copyright Statement
This document is the Accepted Manuscript version of a Published Work that appeared in final form in Crystal Growth & Design, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.cgd.6b01656.