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EM∩IM : software for relating ion mobility mass spectrometry and electron microscopy data.

Degiacomi, M.T. and Benesch, J.L.P. (2016) 'EM∩IM : software for relating ion mobility mass spectrometry and electron microscopy data.', Analyst., 141 (1). pp. 70-75.

Abstract

We present EM∩IM, software that allows the calculation of collision cross-sections from electron density maps obtained for example by means of transmission electron microscopy. This allows the assessment of structures other than those described by atomic coordinates with ion mobility mass spectrometry data, and provides a new means for contouring and validating electron density maps. EM∩IM thereby facilitates the use of data obtained in the gas phase within structural biology studies employing diverse experimental methodologies.

Item Type:Article
Full text:(AM) Accepted Manuscript
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Status:Peer-reviewed
Publisher Web site:https://doi.org/10.1039/c5an01636c
Date accepted:23 November 2015
Date deposited:08 August 2017
Date of first online publication:23 November 2015
Date first made open access:No date available

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