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Long noncoding RNAs involved in resistance to Verticillium dahliae, a fungal disease in cotton.

Zhang, L. and Wang, M. and Li, N. and Wang, H. and Qiu, P. and Hu, Q. and Pei, L. and Xu, Z. and Wang, T. and Gao, E. and Liu, J. and Liu, S. and Hu, Q. and Miao, Y. and Lindsey, K. and Tu, L. and Zhu, L. and Zhang, X. (2018) 'Long noncoding RNAs involved in resistance to Verticillium dahliae, a fungal disease in cotton.', Plant biotechnology journal., 16 (6). pp. 1172-1185.


Long non-coding RNAs (lncRNAs) have several known functions in plant development, but their possible roles in responding to plant disease remain largely unresolved. In this study, we described a comprehensive disease-responding lncRNA profiles in defense against a cotton fungal disease Verticillium dahliae. We further revealed the conserved and specific characters of disease responding process between two cotton species. Conservatively for two cotton species, we found the expression dominance of induced lncRNAs in the Dt subgenome, indicating a biased induction pattern in the co-existing subgenomes of allotetraploid cotton. Comparative analysis of lncRNA expression and their proposed functions in resistant Gossypium barbadense cv. ‘7124′ versus susceptible G. hirsutum cv. ‘YZ1′ revealed their distinct disease response mechanisms. Species-specific (LS) lncRNAs containing more SNPs displayed a fiercer inducing level post infection than the species-conserved (core) lncRNAs. Gene Ontology enrichment of LS lncRNAs and core lncRNAs indicates distinct roles in the process of biotic stimulus. Further functional analysis showed that two core lncRNAs GhlncNAT-ANX2- and GhlncNAT-RLP7- silenced seedlings displayed an enhanced resistance towards V. dahliae and Botrytis cinerea, possibly associated with the increased expression of LOX1 and LOX2. This study represents the first characterization of lncRNAs involved in resistance to fungal disease and provides new clues to elucidate cotton disease response mechanism.

Item Type:Article
Full text:(AM) Accepted Manuscript
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Full text:(VoR) Version of Record
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Publisher statement:© 2017 The Authors. Plant Biotechnology Journal published by Society for Experimental Biology and The Association of Applied Biologists and John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Date accepted:01 November 2017
Date deposited:28 November 2017
Date of first online publication:21 December 2017
Date first made open access:No date available

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