Parker, D. and Williams, J. A. G. and Walter, E. R. H. (2018) 'Tuning Mg2+ selectivity : comparative analysis of the photophysical properties of four fluorescent probes with an alkynyl-naphthalene fluorophore.', Chemistry : a European journal., 24 (24). pp. 6432-6441.
Four alkynyl‐1‐naphthyl fluorophores have been synthesised with tri‐ or pentadentate ligating groups suited to the binding of magnesium. Their photophysical and binding properties for magnesium, calcium and zinc ions have been assessed using absorption, emission and excitation spectroscopy. Each compound has a pKa value between 6.2 and 5.1 and exhibits no significant pH response around pH 7.2. Enhanced selectivity for Mg2+ over Ca2+ was observed with a pentadentate phosphinate substituted system, compared to its carboxylate analogue, due to a 10‐fold lowering of affinity for the Ca2+ ion. In each case, the overall dissociation constants for Mg2+ fall in the low mM range.
|Full text:||(AM) Accepted Manuscript|
Download PDF (1097Kb)
|Publisher Web site:||https://doi.org/10.1002/chem.201800013|
|Publisher statement:||This is the peer reviewed version of the following article: Parker, D., Williams, J. A. G. & Walter, E. R. H. (2018). Tuning Mg2+ selectivity: comparative analysis of the photophysical properties of four fluorescent probes with an alkynyl-naphthalene fluorophore. Chemistry - A European Journal, which has been published in final form at https://doi.org/10.1002/chem.201800013. This article may be used for non-commercial purposes in accordance With Wiley-VCH Terms and Conditions for self-archiving.|
|Date accepted:||28 February 2018|
|Date deposited:||23 March 2018|
|Date of first online publication:||28 January 2018|
|Date first made open access:||28 January 2019|
Save or Share this output
|Look up in GoogleScholar|