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VasoTracker, a low-cost and open source pressure myograph system for vascular physiology.

Lawton, Penelope F. and Lee, Matthew D. and Saunter, Christopher D. and Girkin, John M. and McCarron, John G. and Wilson, Calum (2019) 'VasoTracker, a low-cost and open source pressure myograph system for vascular physiology.', Frontiers in physiology., 10 . p. 99.

Abstract

Pressure myography, one of the most commonly used techniques in vascular research, measures the diameter of isolated, pressurized arteries to assess the functional activity of smooth muscle and endothelial cells. Despite the widespread adoption of this technique for assessing vascular function, there are only a small number of commercial systems and these are expensive. Here, we introduce a complete, open source pressure myograph system and analysis software, VasoTracker, that can be set-up for approximately 10% of the cost of commercial alternatives. We report on the development of VasoTracker and demonstrate its ability to assess various components of vascular reactivity. A unique feature of the VasoTracker platform is the publicly accessible website (http://www.vasotracker.com/) that documents how to assemble and use this affordable, adaptable, and expandable pressure myograph.

Item Type:Article
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Available under License - Creative Commons Attribution.
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Status:Peer-reviewed
Publisher Web site:https://doi.org/10.3389/fphys.2019.00099
Publisher statement:Copyright © 2019 Lawton, Lee, Saunter, Girkin, McCarron and Wilson. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Date accepted:28 January 2019
Date deposited:21 February 2019
Date of first online publication:21 February 2019
Date first made open access:21 February 2019

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