Meksawangwong, Sureemas and Gohil, Bhavini and Punyain, Wikorn and Pal, Robert and Kielar, Filip (2019) 'Synthesis and investigation of a tris-cyclometalated iridium complex bearing a single quarternary ammonium group.', Inorganica chimica acta., 497 . p. 119066.
Abstract
A novel tris-cyclometalated iridium complex (1) containing a single quarternary ammonium moiety has been synthesized, characterized, and investigated as a potential cellular imaging probe. The complex is the next generation of the aminoalkyl iridium complexes recently published by our group. The complex possesses outstanding photophysical properties. The complex is stable in solution in dark but exhibits rapid photocatalyzed transformations. Investigations of this behavior have shown that these transformations involve the formation of an electrophilic species, which can be captured by a suitable nucleophile, leading to the formation of new product. The complex has also been investigated as a potential cellular stain. It is less cytotoxic than its aminoalkyl predecessor and shows lysosomal localization as its precursor.
| Item Type: | Article |
|---|---|
| Full text: | (AM) Accepted Manuscript Available under License - Creative Commons Attribution Non-commercial No Derivatives. Download PDF (505Kb) |
| Status: | Peer-reviewed |
| Publisher Web site: | https://doi.org/10.1016/j.ica.2019.119066 |
| Publisher statement: | © 2019 This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| Date accepted: | 08 August 2019 |
| Date deposited: | 05 September 2019 |
| Date of first online publication: | 10 August 2019 |
| Date first made open access: | 10 August 2020 |
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