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Exploiting C-H borylation for the multidirectional elaboration of 2-halopyridines.

Reuven, J.A. and Salih, O.A. and Sadler, S.A. and Thomas, C.L. and Steel, P.G. (2020) 'Exploiting C-H borylation for the multidirectional elaboration of 2-halopyridines.', Tetrahedron, 76 (3). p. 29723.

Abstract

Regioselectively polysubstituted pyridines can be efficiently accessed from 2-halopyridines via a sequence involving C-H borylation, Suzuki-Miyaura cross-coupling and nucleophilic aromatic substitution chemistry.

Item Type:Article
Full text:(AM) Accepted Manuscript
Available under License - Creative Commons Attribution Non-commercial No Derivatives.
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Status:Peer-reviewed
Publisher Web site:https://doi.org/10.1016/j.tet.2019.130836
Publisher statement:© 2019 This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
Date accepted:25 November 2019
Date deposited:26 November 2019
Date of first online publication:29 November 2019
Date first made open access:29 November 2020

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