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Light microscopy of the endoplasmic reticulum‐membrane contact sites in plants.

Zang, J. and Zhang, T. and Hussey, P.J. and Wang, P. (2020) 'Light microscopy of the endoplasmic reticulum‐membrane contact sites in plants.', Journal of microscopy., 280 (2). pp. 134-139.


The existence of membrane contact sites (MCS) has been reported in different systems in the past decade, and their importance has been recognized by the cell biology community. Amongst all endomembrane structures, the endoplasmic reticulum (ER) plays vital roles in organizing the organelle interaction network with the plasma membrane (PM), Golgi bodies, mitochondria, plastids, endosomes and autophagosomes. A number of methods have been used to study the establishment and functions of these interactions, among them, light microscopy appears to be one of the most effective approaches. Here, we present an overview of the discovery of ER‐PM contact sites, and highlight the latest developments in light microscopical‐based techniques that can be used for their study.

Item Type:Article
Full text:(AM) Accepted Manuscript
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Publisher statement:This is the peer reviewed version of the following article: Zang, J., Zhang, T., Hussey, P.J. & Wang, P. (2020). Light microscopy of the endoplasmic reticulum‐membrane contact sites in plants. Journal of Microscopy 280(2): 134-139, which has been published in final form at This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
Date accepted:02 June 2020
Date deposited:09 June 2020
Date of first online publication:16 June 2020
Date first made open access:16 June 2021

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