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Translating cell biology of ageing? On the importance of choreographing knowledge

Moreira, Tiago

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Abstract

This paper describes and explores how translational research models, embedded in institutions and standards, interact with the epistemic and material practices of cell biologists of ageing, a field re-energized by emergent technoscientific promises that hinge on the possibility of eliminating or manipulating senescent cells to tackle age-related diseases. Drawing on a 3-year long lab ethnography, the paper suggests that knowledge making in cell biology of ageing relies on two different epistemic and material cultures, to then argue that these cultures combine in four different types of experimental systems, only one of which can properly be seen as pertaining to translation as usually conceived. The paper further analyses how cell biologists articulate the linear temporality of translational research with the unfolding experimental chains where, by shifting between types of experimental system, cell biologists are able to generatively reconfigure their epistemic objects, and the consequences of this fragile arrangements for the field.

Citation

Moreira, T. (2021). Translating cell biology of ageing? On the importance of choreographing knowledge. New Genetics and Society, 40(3), 267-283. https://doi.org/10.1080/14636778.2020.1825932

Journal Article Type Article
Acceptance Date Sep 15, 2020
Online Publication Date Sep 26, 2020
Publication Date 2021
Deposit Date Oct 8, 2020
Publicly Available Date Sep 26, 2021
Journal New Genetics and Society
Print ISSN 1463-6778
Electronic ISSN 1469-9915
Publisher Taylor and Francis Group
Peer Reviewed Peer Reviewed
Volume 40
Issue 3
Pages 267-283
DOI https://doi.org/10.1080/14636778.2020.1825932

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