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Temperature Gradient Interaction Chromatography: A Perspective

Hutchings, Lian R. and Pagliarulo, Antonella (2021) 'Temperature Gradient Interaction Chromatography: A Perspective.', Chromatographia, 84 (9). pp. 813-818.


The application of temperature gradient interaction chromatography (TGIC) as an advanced technique for the characterisation of polymers is discussed, in comparison to other liquid chromatography techniques and in particular the ubiquitous size exclusion chromatography. Specifically, the use of reversed-phase TGIC for the interrogation of complex branched polymers and normal-phase TGIC for characterisation of high-molar mass end-functionalised polymers is highlighted.

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Publisher statement:Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit
Date accepted:06 July 2021
Date deposited:02 August 2021
Date of first online publication:14 July 2021
Date first made open access:02 August 2021

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