We use cookies to ensure that we give you the best experience on our website. By continuing to browse this repository, you give consent for essential cookies to be used. You can read more about our Privacy and Cookie Policy.

Durham Research Online
You are in:

Efficient Emulation of Computer Models Utilising Multiple Known Boundaries of Differing Dimension

Jackson, Samuel E. and Vernon, Ian (2022) 'Efficient Emulation of Computer Models Utilising Multiple Known Boundaries of Differing Dimension.', Bayesian Analysis .


Emulation has been successfully applied across a wide variety of scientific disciplines for efficiently analysing computationally intensive models. We develop known boundary emulation strategies which utilise the fact that, for many computer models, there exist hyperplanes in the input parameter space for which the model output can be evaluated far more efficiently, whether this be analytically or just significantly faster using a more efficient and simpler numerical solver. The information contained on these known hyperplanes, or boundaries, can be incorporated into the emulation process via analytical update, thus involving no additional computational cost. In this article, we show that such analytical updates are available for multiple boundaries of various dimensions. We subsequently demonstrate which configurations of boundaries such analytical updates are available for, in particular by presenting a set of conditions that such a set of boundaries must satisfy. We demonstrate the powerful computational advantages of the known boundary emulation techniques developed on both an illustrative low-dimensional simulated example and a scientifically relevant and high-dimensional systems biology model of hormonal crosstalk in the roots of an Arabidopsis plant.

Item Type:Article
Full text:Publisher-imposed embargo
(AM) Accepted Manuscript
File format - PDF
Publisher Web site:
Date accepted:06 January 2022
Date deposited:28 January 2022
Date of first online publication:2022
Date first made open access:No date available

Save or Share this output

Look up in GoogleScholar